A negative blood type characteristics
Bone-marrow transplants are performed for many leukemias and lymphomas, among other diseases. Another more common cause of blood type change is a bone marrow transplant. Almost always, an individual has the same blood group for life, but very rarely an individual's blood type changes through addition or suppression of an antigen in infection, malignancy, or autoimmune disease. The two most important blood group systems are ABO and Rh they determine someone's blood type (A, B, AB, and O, with + or - denoting RhD status) for suitability in blood transfusion.Ī complete blood type would describe each of the 43 blood groups, and an individual's blood type is one of many possible combinations of blood-group antigens. As of 2021, a total of 43 human blood group systems are recognized by the International Society of Blood Transfusion (ISBT). īlood types are inherited and represent contributions from both parents of an individual. Several of these red blood cell surface antigens can stem from one allele (or an alternative version of a gene) and collectively form a blood group system. Some of these antigens are also present on the surface of other types of cells of various tissues. These antigens may be proteins, carbohydrates, glycoproteins, or glycolipids, depending on the blood group system. Blood type (or blood group) is determined, in part, by the ABO blood group antigens present on red blood cells.Ī blood type (also known as a blood group) is a classification of blood, based on the presence and absence of antibodies and inherited antigenic substances on the surface of red blood cells (RBCs).